P2 receptors and immunity

Immune cells express receptors for extracellular nucleotides named P2 receptors. P2 receptors transduce signals delivered by nucleotides present in the extracellular environment. Accruing evidence shows that purinergic signalling has a profound effect on multiple immune cell responses such as T lymp...

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Detalles Bibliográficos
Autores principales: Rayah, Amel, Kanellopoulos, Jean M., Di Virgilio, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3514633/
https://www.ncbi.nlm.nih.gov/pubmed/22909902
http://dx.doi.org/10.1016/j.micinf.2012.07.006
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author Rayah, Amel
Kanellopoulos, Jean M.
Di Virgilio, Francesco
author_facet Rayah, Amel
Kanellopoulos, Jean M.
Di Virgilio, Francesco
author_sort Rayah, Amel
collection PubMed
description Immune cells express receptors for extracellular nucleotides named P2 receptors. P2 receptors transduce signals delivered by nucleotides present in the extracellular environment. Accruing evidence shows that purinergic signalling has a profound effect on multiple immune cell responses such as T lymphocyte proliferation, chemotaxis, cytokine release, phagocytosis, Ag presentation and cytotoxicity. This makes P2 receptors an attractive target for the therapy of immuno-mediated disease and cancer.
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spelling pubmed-35146332012-12-05 P2 receptors and immunity Rayah, Amel Kanellopoulos, Jean M. Di Virgilio, Francesco Microbes Infect Article Immune cells express receptors for extracellular nucleotides named P2 receptors. P2 receptors transduce signals delivered by nucleotides present in the extracellular environment. Accruing evidence shows that purinergic signalling has a profound effect on multiple immune cell responses such as T lymphocyte proliferation, chemotaxis, cytokine release, phagocytosis, Ag presentation and cytotoxicity. This makes P2 receptors an attractive target for the therapy of immuno-mediated disease and cancer. Elsevier 2012-11 /pmc/articles/PMC3514633/ /pubmed/22909902 http://dx.doi.org/10.1016/j.micinf.2012.07.006 Text en © 2012 Elsevier Masson SAS. This document may be redistributed and reused, subject to certain conditions (http://www.elsevier.com/wps/find/authorsview.authors/supplementalterms1.0) .
spellingShingle Article
Rayah, Amel
Kanellopoulos, Jean M.
Di Virgilio, Francesco
P2 receptors and immunity
title P2 receptors and immunity
title_full P2 receptors and immunity
title_fullStr P2 receptors and immunity
title_full_unstemmed P2 receptors and immunity
title_short P2 receptors and immunity
title_sort p2 receptors and immunity
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3514633/
https://www.ncbi.nlm.nih.gov/pubmed/22909902
http://dx.doi.org/10.1016/j.micinf.2012.07.006
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AT kanellopoulosjeanm p2receptorsandimmunity
AT divirgiliofrancesco p2receptorsandimmunity

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