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Sex-biased genetic effects on gene regulation in humans

Human regulatory variation, reported as expression quantitative trait loci (eQTLs), contributes to differences between populations and tissues. The contribution of eQTLs to differences between sexes, however, has not been investigated to date. Here we explore regulatory variation in females and male...

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Detalles Bibliográficos
Autores principales: Dimas, Antigone S., Nica, Alexandra C., Montgomery, Stephen B., Stranger, Barbara E., Raj, Towfique, Buil, Alfonso, Giger, Thomas, Lappalainen, Tuuli, Gutierrez-Arcelus, Maria, McCarthy, Mark I., Dermitzakis, Emmanouil T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3514666/
https://www.ncbi.nlm.nih.gov/pubmed/22960374
http://dx.doi.org/10.1101/gr.134981.111