CpG islands and GC content dictate nucleosome depletion in a transcription-independent manner at mammalian promoters

One clear hallmark of mammalian promoters is the presence of CpG islands (CGIs) at more than two-thirds of genes, whereas TATA boxes are only present at a minority of promoters. Using genome-wide approaches, we show that GC content and CGIs are major promoter elements in mammalian cells, able to gov...

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Detalles Bibliográficos
Autores principales: Fenouil, Romain, Cauchy, Pierre, Koch, Frederic, Descostes, Nicolas, Cabeza, Joaquin Zacarias, Innocenti, Charlène, Ferrier, Pierre, Spicuglia, Salvatore, Gut, Marta, Gut, Ivo, Andrau, Jean-Christophe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3514669/
https://www.ncbi.nlm.nih.gov/pubmed/23100115
http://dx.doi.org/10.1101/gr.138776.112

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