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Genome-wide mapping of nucleosome positioning and DNA methylation within individual DNA molecules

DNA methylation and nucleosome positioning work together to generate chromatin structures that regulate gene expression. Nucleosomes are typically mapped using nuclease digestion requiring significant amounts of material and varying enzyme concentrations. We have developed a method (NOMe-seq) that u...

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Detalles Bibliográficos
Autores principales: Kelly, Theresa K., Liu, Yaping, Lay, Fides D., Liang, Gangning, Berman, Benjamin P., Jones, Peter A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3514679/
https://www.ncbi.nlm.nih.gov/pubmed/22960375
http://dx.doi.org/10.1101/gr.143008.112