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Development of a Flow Cytometry Live Cell Assay for the Screening of Inhibitors of Hepatitis C Virus (HCV) Replication
In this study, we established a flow cytometry live cell-based assay that permits the screening of hepatitis C virus (HCV) inhibitors. Specifically, we created a stable cell line, which harbors a subgenomic replicon encoding an NS5A-YFP fusion protein. This system allows direct measurement of YFP fl...
Autores principales: | Garcia-Rivera, Jose A, Lin, Kai, Hopkins, Sam, Gregory, Matthew A, Wilkinson, Barrie, Gallay, Philippe A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Bentham Open
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3514710/ https://www.ncbi.nlm.nih.gov/pubmed/23230455 http://dx.doi.org/10.2174/1874357901206010097 |
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