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Intermediate state trapping of a voltage sensor

Voltage sensor domains (VSDs) regulate ion channels and enzymes by undergoing conformational changes depending on membrane electrical signals. The molecular mechanisms underlying the VSD transitions are not fully understood. Here, we show that some mutations of I241 in the S1 segment of the Shaker K...

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Detalles Bibliográficos
Autores principales:	Lacroix, Jérôme J., Pless, Stephan A., Maragliano, Luca, Campos, Fabiana V., Galpin, Jason D., Ahern, Christopher A., Roux, Benoît, Bezanilla, Francisco
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3514728/ https://www.ncbi.nlm.nih.gov/pubmed/23183699 http://dx.doi.org/10.1085/jgp.201210827

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