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Mutual antagonism between IP(3)RII and miRNA-133a regulates calcium signals and cardiac hypertrophy

Inositol 1,4,5′-triphosphate receptor II (IP(3)RII) calcium channel expression is increased in both hypertrophic failing human myocardium and experimentally induced models of the disease. The ectopic calcium released from these receptors induces pro-hypertrophic gene expression and may promote arrhy...

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Detalles Bibliográficos
Autores principales:	Drawnel, Faye M., Wachten, Dagmar, Molkentin, Jeffery D., Maillet, Marjorie, Aronsen, Jan Magnus, Swift, Fredrik, Sjaastad, Ivar, Liu, Ning, Catalucci, Daniele, Mikoshiba, Katsuhiko, Hisatsune, Chihiro, Okkenhaug, Hanneke, Andrews, Simon R., Bootman, Martin D., Roderick, H. Llewelyn
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2012
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3514786/ https://www.ncbi.nlm.nih.gov/pubmed/23166348 http://dx.doi.org/10.1083/jcb.201111095

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