Synthesis of Hemopressin Peptides by Classical Solution Phase Fragment Condensation

A fragment condensation solution phase assembly of the naturally occurring CB(1) inverse agonist nonapeptides, Pro-Val-Asn-Phe-Lys-Phe/Leu-Leu-Ser-His-OH (hemopressins), and two other homologues: N-terminal 2-amino acid (dipeptide) extended undecapeptide, Val-Asp-Pro-Val-Asn-Phe-Lys-Leu-Leu-Ser-His-...

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Detalles Bibliográficos
Autores principales: Reddy, P. Anantha, Jones, Sean T., Lewin, Anita H., Carroll, F. Ivy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3514820/
https://www.ncbi.nlm.nih.gov/pubmed/23227057
http://dx.doi.org/10.1155/2012/186034
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author Reddy, P. Anantha
Jones, Sean T.
Lewin, Anita H.
Carroll, F. Ivy
author_facet Reddy, P. Anantha
Jones, Sean T.
Lewin, Anita H.
Carroll, F. Ivy
author_sort Reddy, P. Anantha
collection PubMed
description A fragment condensation solution phase assembly of the naturally occurring CB(1) inverse agonist nonapeptides, Pro-Val-Asn-Phe-Lys-Phe/Leu-Leu-Ser-His-OH (hemopressins), and two other homologues: N-terminal 2-amino acid (dipeptide) extended undecapeptide, Val-Asp-Pro-Val-Asn-Phe-Lys-Leu-Leu-Ser-His-OH, and three-amino acid (tripeptide) extended dodecapeptide, Arg-Val-Asp-Pro-Val-Asn-Phe-Lys-Leu-Leu-Ser-His-OH, both CB(1) agonists, is reported.
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spelling pubmed-35148202012-12-07 Synthesis of Hemopressin Peptides by Classical Solution Phase Fragment Condensation Reddy, P. Anantha Jones, Sean T. Lewin, Anita H. Carroll, F. Ivy Int J Pept Research Article A fragment condensation solution phase assembly of the naturally occurring CB(1) inverse agonist nonapeptides, Pro-Val-Asn-Phe-Lys-Phe/Leu-Leu-Ser-His-OH (hemopressins), and two other homologues: N-terminal 2-amino acid (dipeptide) extended undecapeptide, Val-Asp-Pro-Val-Asn-Phe-Lys-Leu-Leu-Ser-His-OH, and three-amino acid (tripeptide) extended dodecapeptide, Arg-Val-Asp-Pro-Val-Asn-Phe-Lys-Leu-Leu-Ser-His-OH, both CB(1) agonists, is reported. Hindawi Publishing Corporation 2012 2012-11-27 /pmc/articles/PMC3514820/ /pubmed/23227057 http://dx.doi.org/10.1155/2012/186034 Text en Copyright © 2012 P. Anantha Reddy et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Reddy, P. Anantha
Jones, Sean T.
Lewin, Anita H.
Carroll, F. Ivy
Synthesis of Hemopressin Peptides by Classical Solution Phase Fragment Condensation
title Synthesis of Hemopressin Peptides by Classical Solution Phase Fragment Condensation
title_full Synthesis of Hemopressin Peptides by Classical Solution Phase Fragment Condensation
title_fullStr Synthesis of Hemopressin Peptides by Classical Solution Phase Fragment Condensation
title_full_unstemmed Synthesis of Hemopressin Peptides by Classical Solution Phase Fragment Condensation
title_short Synthesis of Hemopressin Peptides by Classical Solution Phase Fragment Condensation
title_sort synthesis of hemopressin peptides by classical solution phase fragment condensation
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3514820/
https://www.ncbi.nlm.nih.gov/pubmed/23227057
http://dx.doi.org/10.1155/2012/186034
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