N,N′-bis­[(3-hy­droxy-4(4H)-oxypyran-2-yl)meth­yl]-N,N′-dimethyl­ethylene-1,2-diammonium tetra­chloridoplatinate(II) dihydrate

The title compound (C(16)H(22)N(2)O(6))[PtCl(4)]·2H(2)O, shows anti­proliferative activity in eight tumor cell lines. The asymmetric unit consists of one solvent water mol­ecule on a general position, and one half of each of the polyammonium cation and the tetrachloridoplatinate(II) anion, both of t...

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Autores principales: Fusi, Vieri, Giorgi, Luca, Macedi, Eleonora, Paoli, Paola, Rossi, Patrizia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2012
Materias:
Metal-Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3515092/
https://www.ncbi.nlm.nih.gov/pubmed/23284319
http://dx.doi.org/10.1107/S1600536812040949
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author Fusi, Vieri
Giorgi, Luca
Macedi, Eleonora
Paoli, Paola
Rossi, Patrizia
author_facet Fusi, Vieri
Giorgi, Luca
Macedi, Eleonora
Paoli, Paola
Rossi, Patrizia
author_sort Fusi, Vieri
collection PubMed
description The title compound (C(16)H(22)N(2)O(6))[PtCl(4)]·2H(2)O, shows anti­proliferative activity in eight tumor cell lines. The asymmetric unit consists of one solvent water mol­ecule on a general position, and one half of each of the polyammonium cation and the tetrachloridoplatinate(II) anion, both of them located on centers of inversion. In the crystal, the cations are connected via hydrogen bonding between the carbonyl O atoms and the hydroxyl H atoms into zigzag chains that elongate in the c-axis direction. In addition, the carbonyl O atom is hydrogen-bonded to the water mol­ecule which, in turn, inter­acts with the [PtCl(4)](2−) anion. Finally, the chains are linked by N—H(+)⋯Cl inter­actions into a three-dimensional network.
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spelling pubmed-35150922013-01-02 N,N′-bis­[(3-hy­droxy-4(4H)-oxypyran-2-yl)meth­yl]-N,N′-dimethyl­ethylene-1,2-diammonium tetra­chloridoplatinate(II) dihydrate Fusi, Vieri Giorgi, Luca Macedi, Eleonora Paoli, Paola Rossi, Patrizia Acta Crystallogr Sect E Struct Rep Online Metal-Organic Papers The title compound (C(16)H(22)N(2)O(6))[PtCl(4)]·2H(2)O, shows anti­proliferative activity in eight tumor cell lines. The asymmetric unit consists of one solvent water mol­ecule on a general position, and one half of each of the polyammonium cation and the tetrachloridoplatinate(II) anion, both of them located on centers of inversion. In the crystal, the cations are connected via hydrogen bonding between the carbonyl O atoms and the hydroxyl H atoms into zigzag chains that elongate in the c-axis direction. In addition, the carbonyl O atom is hydrogen-bonded to the water mol­ecule which, in turn, inter­acts with the [PtCl(4)](2−) anion. Finally, the chains are linked by N—H(+)⋯Cl inter­actions into a three-dimensional network. International Union of Crystallography 2012-10-06 /pmc/articles/PMC3515092/ /pubmed/23284319 http://dx.doi.org/10.1107/S1600536812040949 Text en © Fusi et al. 2012 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Metal-Organic Papers
Fusi, Vieri
Giorgi, Luca
Macedi, Eleonora
Paoli, Paola
Rossi, Patrizia
N,N′-bis­[(3-hy­droxy-4(4H)-oxypyran-2-yl)meth­yl]-N,N′-dimethyl­ethylene-1,2-diammonium tetra­chloridoplatinate(II) dihydrate
title N,N′-bis­[(3-hy­droxy-4(4H)-oxypyran-2-yl)meth­yl]-N,N′-dimethyl­ethylene-1,2-diammonium tetra­chloridoplatinate(II) dihydrate
title_full N,N′-bis­[(3-hy­droxy-4(4H)-oxypyran-2-yl)meth­yl]-N,N′-dimethyl­ethylene-1,2-diammonium tetra­chloridoplatinate(II) dihydrate
title_fullStr N,N′-bis­[(3-hy­droxy-4(4H)-oxypyran-2-yl)meth­yl]-N,N′-dimethyl­ethylene-1,2-diammonium tetra­chloridoplatinate(II) dihydrate
title_full_unstemmed N,N′-bis­[(3-hy­droxy-4(4H)-oxypyran-2-yl)meth­yl]-N,N′-dimethyl­ethylene-1,2-diammonium tetra­chloridoplatinate(II) dihydrate
title_short N,N′-bis­[(3-hy­droxy-4(4H)-oxypyran-2-yl)meth­yl]-N,N′-dimethyl­ethylene-1,2-diammonium tetra­chloridoplatinate(II) dihydrate
title_sort n,n′-bis­[(3-hy­droxy-4(4h)-oxypyran-2-yl)meth­yl]-n,n′-dimethyl­ethylene-1,2-diammonium tetra­chloridoplatinate(ii) dihydrate
topic Metal-Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3515092/
https://www.ncbi.nlm.nih.gov/pubmed/23284319
http://dx.doi.org/10.1107/S1600536812040949
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