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N-[2-(5-Bromo-2-morpholin-4-ylpyrim­idin-4-ylsulfan­yl)-4-meth­oxy­phen­yl]-2,4,6-trimethyl­benzene­sulfonamide

In the title compound, C(24)H(27)BrN(4)O(4)S(2), the mol­ecule is twisted at the sulfonyl S atom with a C—S(O(2))—N(H)—C torsion angle of 62.6 (3)°. The benzene rings bridged by the sulfonamide group are tilted to each other by a dihedral angle of 60.6 (1)°. The dihedral angle between the sulfur-bri...

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Detalles Bibliográficos
Autores principales: Kumar, Mohan, Mallesha, L., Sridhar, M. A., Kapoor, Kamini, Gupta, Vivek K., Kant, Rajni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3515169/
https://www.ncbi.nlm.nih.gov/pubmed/23284396
http://dx.doi.org/10.1107/S1600536812040792
Descripción
Sumario:In the title compound, C(24)H(27)BrN(4)O(4)S(2), the mol­ecule is twisted at the sulfonyl S atom with a C—S(O(2))—N(H)—C torsion angle of 62.6 (3)°. The benzene rings bridged by the sulfonamide group are tilted to each other by a dihedral angle of 60.6 (1)°. The dihedral angle between the sulfur-bridged pyrimidine and benzene rings is 62.7 (1)°. The morpholine ring adopts a chair conformation. The mol­ecular conformation is stabilized by a weak intra­molecular π–π stacking inter­action between the pyrimidine and the 2,4,6-trimethyl­benzene rings [centroid–centroid distance = 3.793 (2) Å]. In the crystal, mol­ecules are linked by N—H⋯O hydrogen bonds into a chain along the b axis.