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N-[4-(2-Propyn-1-yloxy)phenyl]acetamide
The title compound, C(11)H(11)NO(2), was synthesized by chemoselective N-acetylation of 4-aminophenol followed by reaction with propargyl bromide in the presence of K(2)CO(3). the acetamide and propyn-1-yloxy substituents form dihedral angles of 18.31 (6) and 7.01 (10)°, respectively, with the ben...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3515179/ https://www.ncbi.nlm.nih.gov/pubmed/23284406 http://dx.doi.org/10.1107/S1600536812041207 |
Sumario: | The title compound, C(11)H(11)NO(2), was synthesized by chemoselective N-acetylation of 4-aminophenol followed by reaction with propargyl bromide in the presence of K(2)CO(3). the acetamide and propyn-1-yloxy substituents form dihedral angles of 18.31 (6) and 7.01 (10)°, respectively, with the benzene ring. In the crystal, molecules are linked by N—H⋯O hydrogen bonds into chains along [010]. C—H⋯O and C—H⋯π interactions also occur. |
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