N-[4-(2-Propyn-1-yl­oxy)phen­yl]acetamide

The title compound, C(11)H(11)NO(2), was synthesized by chemoselective N-acetyl­ation of 4-amino­phenol followed by reaction with propargyl bromide in the presence of K(2)CO(3). the acetamide and propyn-1-yloxy substituents form dihedral angles of 18.31 (6) and 7.01 (10)°, respectively, with the ben...

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Detalles Bibliográficos
Autores principales: Belay, Yonas H., Kinfe, Henok H., Muller, Alfred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2012
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3515179/
https://www.ncbi.nlm.nih.gov/pubmed/23284406
http://dx.doi.org/10.1107/S1600536812041207
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author Belay, Yonas H.
Kinfe, Henok H.
Muller, Alfred
author_facet Belay, Yonas H.
Kinfe, Henok H.
Muller, Alfred
author_sort Belay, Yonas H.
collection PubMed
description The title compound, C(11)H(11)NO(2), was synthesized by chemoselective N-acetyl­ation of 4-amino­phenol followed by reaction with propargyl bromide in the presence of K(2)CO(3). the acetamide and propyn-1-yloxy substituents form dihedral angles of 18.31 (6) and 7.01 (10)°, respectively, with the benzene ring. In the crystal, mol­ecules are linked by N—H⋯O hydrogen bonds into chains along [010]. C—H⋯O and C—H⋯π inter­actions also occur.
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spelling pubmed-35151792013-01-02 N-[4-(2-Propyn-1-yl­oxy)phen­yl]acetamide Belay, Yonas H. Kinfe, Henok H. Muller, Alfred Acta Crystallogr Sect E Struct Rep Online Organic Papers The title compound, C(11)H(11)NO(2), was synthesized by chemoselective N-acetyl­ation of 4-amino­phenol followed by reaction with propargyl bromide in the presence of K(2)CO(3). the acetamide and propyn-1-yloxy substituents form dihedral angles of 18.31 (6) and 7.01 (10)°, respectively, with the benzene ring. In the crystal, mol­ecules are linked by N—H⋯O hydrogen bonds into chains along [010]. C—H⋯O and C—H⋯π inter­actions also occur. International Union of Crystallography 2012-10-06 /pmc/articles/PMC3515179/ /pubmed/23284406 http://dx.doi.org/10.1107/S1600536812041207 Text en © Belay et al. 2012 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Belay, Yonas H.
Kinfe, Henok H.
Muller, Alfred
N-[4-(2-Propyn-1-yl­oxy)phen­yl]acetamide
title N-[4-(2-Propyn-1-yl­oxy)phen­yl]acetamide
title_full N-[4-(2-Propyn-1-yl­oxy)phen­yl]acetamide
title_fullStr N-[4-(2-Propyn-1-yl­oxy)phen­yl]acetamide
title_full_unstemmed N-[4-(2-Propyn-1-yl­oxy)phen­yl]acetamide
title_short N-[4-(2-Propyn-1-yl­oxy)phen­yl]acetamide
title_sort n-[4-(2-propyn-1-yl­oxy)phen­yl]acetamide
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3515179/
https://www.ncbi.nlm.nih.gov/pubmed/23284406
http://dx.doi.org/10.1107/S1600536812041207
work_keys_str_mv AT belayyonash n42propyn1yloxyphenylacetamide
AT kinfehenokh n42propyn1yloxyphenylacetamide
AT mulleralfred n42propyn1yloxyphenylacetamide

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