Exome sequencing of serous endometrial tumors identifies recurrent somatic mutations in chromatin-remodeling and ubiquitin ligase complex genes

Endometrial cancer is the 6(th) most commonly diagnosed cancer among women worldwide, causing ~74,000 deaths annually (1). Serous endometrial cancers are a clinically aggressive subtype with a poorly defined genetic etiology (2-4). We used whole exome sequencing (WES) to comprehensively search for s...

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Detalles Bibliográficos
Autores principales: Le Gallo, Matthieu, O’Hara, Andrea J., Rudd, Meghan L., Urick, Mary Ellen, Hansen, Nancy F., O’Neil, Nigel J., Price, Jessica C., Zhang, Suiyuan, England, Bryant M., Godwin, Andrew K., Sgroi, Dennis C., Hieter, Philip, Mullikin, James C., Merino, Maria J., Bell, Daphne W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3515204/
https://www.ncbi.nlm.nih.gov/pubmed/23104009
http://dx.doi.org/10.1038/ng.2455

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