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2-(1H-Indol-3-yl)acetohydrazide
In the title compound C(10)H(11)N(3)O, the mean plane of the indole ring system (r.m.s. deviation 0.0131 Å) subtends a dihedral angle of 87.27 (5)° to the almost planar acetohydrazide substituent (r.m.s. deviation 0.0291 Å). In the crystal, bifurcated N—H⋯(O,N) and N—H⋯N hydrogen bonds involving the...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3515242/ https://www.ncbi.nlm.nih.gov/pubmed/23284462 http://dx.doi.org/10.1107/S1600536812041694 |
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author | Sidra, Lala Rukh Khan, Islam Ullah Yar, Muhammad Simpson, Jim |
author_facet | Sidra, Lala Rukh Khan, Islam Ullah Yar, Muhammad Simpson, Jim |
author_sort | Sidra, Lala Rukh |
collection | PubMed |
description | In the title compound C(10)H(11)N(3)O, the mean plane of the indole ring system (r.m.s. deviation 0.0131 Å) subtends a dihedral angle of 87.27 (5)° to the almost planar acetohydrazide substituent (r.m.s. deviation 0.0291 Å). In the crystal, bifurcated N—H⋯(O,N) and N—H⋯N hydrogen bonds involving the pyrrole N–H grouping combine to form zigzag chains along a. Additional N—H⋯O contacts from the hydrazide N–H group augmented by C—H⋯π interactions link the molecules into chains along the a axis. The overall effect of these contacts is a three-dimensional network structure with molecules stacked along the b-axis direction. |
format | Online Article Text |
id | pubmed-3515242 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | International Union of Crystallography |
record_format | MEDLINE/PubMed |
spelling | pubmed-35152422013-01-02 2-(1H-Indol-3-yl)acetohydrazide Sidra, Lala Rukh Khan, Islam Ullah Yar, Muhammad Simpson, Jim Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound C(10)H(11)N(3)O, the mean plane of the indole ring system (r.m.s. deviation 0.0131 Å) subtends a dihedral angle of 87.27 (5)° to the almost planar acetohydrazide substituent (r.m.s. deviation 0.0291 Å). In the crystal, bifurcated N—H⋯(O,N) and N—H⋯N hydrogen bonds involving the pyrrole N–H grouping combine to form zigzag chains along a. Additional N—H⋯O contacts from the hydrazide N–H group augmented by C—H⋯π interactions link the molecules into chains along the a axis. The overall effect of these contacts is a three-dimensional network structure with molecules stacked along the b-axis direction. International Union of Crystallography 2012-10-20 /pmc/articles/PMC3515242/ /pubmed/23284462 http://dx.doi.org/10.1107/S1600536812041694 Text en © Sidra et al. 2012 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited. |
spellingShingle | Organic Papers Sidra, Lala Rukh Khan, Islam Ullah Yar, Muhammad Simpson, Jim 2-(1H-Indol-3-yl)acetohydrazide |
title | 2-(1H-Indol-3-yl)acetohydrazide |
title_full | 2-(1H-Indol-3-yl)acetohydrazide |
title_fullStr | 2-(1H-Indol-3-yl)acetohydrazide |
title_full_unstemmed | 2-(1H-Indol-3-yl)acetohydrazide |
title_short | 2-(1H-Indol-3-yl)acetohydrazide |
title_sort | 2-(1h-indol-3-yl)acetohydrazide |
topic | Organic Papers |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3515242/ https://www.ncbi.nlm.nih.gov/pubmed/23284462 http://dx.doi.org/10.1107/S1600536812041694 |
work_keys_str_mv | AT sidralalarukh 21hindol3ylacetohydrazide AT khanislamullah 21hindol3ylacetohydrazide AT yarmuhammad 21hindol3ylacetohydrazide AT simpsonjim 21hindol3ylacetohydrazide |