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Biological characteristics of the rtA181T/sW172* mutant strain of Hepatitis B virus in animal model

BACKGROUND: The effects of Hepatitis B virus (HBV) rtA181T/sW172* mutation on viral replication and pathogenicity was concerned recently. This study aimed to investigate the biological characteristics of rtA181T/sW172* mutant strain of HBV in animal model. METHODS: The rtA181T/sW172* mutant plasmid...

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Detalles Bibliográficos
Autores principales: Dai, Jie, Chen, En-Qiang, Bai, Lang, Gong, Dao-Yin, Zhou, Qiao-Ling, Cheng, Xing, Huang, Fei-Jun, Tang, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3515399/
https://www.ncbi.nlm.nih.gov/pubmed/23171829
http://dx.doi.org/10.1186/1743-422X-9-280