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Elastase and Tryptase Govern TNFα-Mediated Production of Active Chemerin by Adipocytes

Chemerin is a leukocyte chemoattractant and adipokine with important immune and metabolic roles. Chemerin, secreted in an inactive form prochemerin, undergoes C-terminal proteolytic cleavage to generate active chemerin, a ligand for the chemokine-like receptor-1 (CMKLR1). We previously identified th...

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Detalles Bibliográficos
Autores principales:	Parlee, Sebastian D., McNeil, Jenna O., Muruganandan, Shanmugam, Sinal, Christopher J., Goralski, Kerry B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3515524/ https://www.ncbi.nlm.nih.gov/pubmed/23227233 http://dx.doi.org/10.1371/journal.pone.0051072

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