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Quantitative Allele-Specific Expression and DNA Methylation Analysis of H19, IGF2 and IGF2R in the Human Placenta across Gestation Reveals H19 Imprinting Plasticity

Imprinted genes play important roles in placental differentiation, growth and function, with profound effects on fetal development. In humans, H19 and IGF2 are imprinted, but imprinting of IGF2R remains controversial. The H19 non-coding RNA is a negative regulator of placental growth and altered pla...

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Detalles Bibliográficos
Autores principales:	Buckberry, Sam, Bianco-Miotto, Tina, Hiendleder, Stefan, Roberts, Claire T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3515552/ https://www.ncbi.nlm.nih.gov/pubmed/23227253 http://dx.doi.org/10.1371/journal.pone.0051210

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