A Single Lys Residue on the First Intracellular Loop Modulates the Endoplasmic Reticulum Export and Cell-Surface Expression of α(2A)-Adrenergic Receptor

Export from the endoplasmic reticulum (ER) represents an initial step in intracellular trafficking of G protein-coupled receptors (GPCRs). However, the underlying molecular mechanisms remain poorly understood. We have previously demonstrated that a highly conserved Leu residue on the first intracell...

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Detalles Bibliográficos
Autores principales: Fan, Yi, Li, Chunman, Guo, Jianhui, Hu, Gang, Wu, Guangyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3515576/
https://www.ncbi.nlm.nih.gov/pubmed/23227171
http://dx.doi.org/10.1371/journal.pone.0050416

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