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Cardiac Ankyrin Repeat Protein Attenuates Cardiac Hypertrophy by Inhibition of ERK1/2 and TGF-β Signaling Pathways

AIMS: It has been reported that cardiac ankyrin repeat protein is associated with heart development and diseases. This study is aimed to investigate the role of CARP in heart hypertrophy in vivo. METHODS AND RESULTS: We generated a cardiac-specific CARP-overexpressing transgenic mouse. Although such...

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Detalles Bibliográficos
Autores principales: Song, Yao, Xu, Jialin, Li, Yanfeng, Jia, Chunshi, Ma, Xiaowei, Zhang, Lei, Xie, Xiaojie, Zhang, Yong, Gao, Xiang, Zhang, Youyi, Zhu, Dahai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3515619/
https://www.ncbi.nlm.nih.gov/pubmed/23227174
http://dx.doi.org/10.1371/journal.pone.0050436

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