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Cardiac Ankyrin Repeat Protein Attenuates Cardiac Hypertrophy by Inhibition of ERK1/2 and TGF-β Signaling Pathways
AIMS: It has been reported that cardiac ankyrin repeat protein is associated with heart development and diseases. This study is aimed to investigate the role of CARP in heart hypertrophy in vivo. METHODS AND RESULTS: We generated a cardiac-specific CARP-overexpressing transgenic mouse. Although such...
Autores principales: | Song, Yao, Xu, Jialin, Li, Yanfeng, Jia, Chunshi, Ma, Xiaowei, Zhang, Lei, Xie, Xiaojie, Zhang, Yong, Gao, Xiang, Zhang, Youyi, Zhu, Dahai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3515619/ https://www.ncbi.nlm.nih.gov/pubmed/23227174 http://dx.doi.org/10.1371/journal.pone.0050436 |
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