Interactions Between Wildtype and Mutant Ras Genes in Lung and Skin Carcinogenesis

Ras oncogenes (Hras, Kras, and Nras) are important drivers of carcinogenesis. However, tumors with Ras mutations often show loss of the corresponding wildtype (WT) allele, suggesting that proto-oncogenic forms of Ras can function as a suppressor of carcinogenesis. In vitro studies also suggest that...

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Detalles Bibliográficos
Autores principales: To, Minh D., Del Rosario, Reyno, Westcott, Peter M. K., Banta, Karl L., Balmain, Allan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3515692/
https://www.ncbi.nlm.nih.gov/pubmed/22945650
http://dx.doi.org/10.1038/onc.2012.404

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3515692/
https://www.ncbi.nlm.nih.gov/pubmed/22945650
http://dx.doi.org/10.1038/onc.2012.404

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