ATPase-dependent role of the atypical kinase Rio2 on the evolving pre-40S subunit

Ribosome synthesis involves dynamic association of ribosome biogenesis factors with evolving pre-ribosomal particles. Rio2 is an atypical protein kinase required for pre-40S subunit maturation. We report the crystal structure of eukaryotic Rio2 with bound ATP/Mg(2+). Unexpectedly, the structure reve...

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Detalles Bibliográficos
Autores principales: Ferreira-Cerca, Sébastien, Sagar, Vatsala, Schäfer, Thorsten, Diop, Momar, Wesseling, Anne-Maria, Lu, Haiyun, Chai, Eileen, Hurt, Ed, LaRonde-LeBlanc, Nicole
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3515705/
https://www.ncbi.nlm.nih.gov/pubmed/23104056
http://dx.doi.org/10.1038/nsmb.2403

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3515705/
https://www.ncbi.nlm.nih.gov/pubmed/23104056
http://dx.doi.org/10.1038/nsmb.2403

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