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Increased Inflammation in Atherosclerotic Lesions of Diabetic Akita-LDLr (−/−) Mice Compared to Nondiabetic LDLr (−/−) Mice

Background. Diabetes is associated with increased cardiovascular disease, but the underlying cellular and molecular mechanisms are poorly understood. One proposed mechanism is that diabetes aggravates atherosclerosis by enhancing plaque inflammation. The Akita mouse has recently been adopted as a re...

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Detalles Bibliográficos
Autores principales: Engelbertsen, Daniel, To, Fong, Dunér, Pontus, Kotova, Olga, Söderberg, Ingrid, Alm, Ragnar, Gomez, Maria F., Nilsson, Jan, Bengtsson, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3515907/
https://www.ncbi.nlm.nih.gov/pubmed/23243415
http://dx.doi.org/10.1155/2012/176162