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Analyzing Thiol-Dependent Redox Networks in the Presence of Methylene Blue and Other Antimalarial Agents with RT-PCR-Supported in silico Modeling

BACKGROUND: In the face of growing resistance in malaria parasites to drugs, pharmacological combination therapies are important. There is accumulating evidence that methylene blue (MB) is an effective drug against malaria. Here we explore the biological effects of both MB alone and in combination t...

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Detalles Bibliográficos
Autores principales: Zirkel, J., Cecil, A., Schäfer, F., Rahlfs, S., Ouedraogo, A., Xiao, K., Sawadogo, S., Coulibaly, B., Becker, K., Dandekar, T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Libertas Academica 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3516044/
https://www.ncbi.nlm.nih.gov/pubmed/23236254
http://dx.doi.org/10.4137/BBI.S10193