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Testing of Novel Dengue Virus 2 Vaccines in African Green Monkeys: Safety, Immunogenicity, and Efficacy
The immunogenicity and safety of three novel host-range vaccines containing deletions in the transmembrane domain of dengue virus serotype 2 (DV2) E glycoprotein were evaluated in African green monkeys. The shorter transmembrane domains are capable of functionally spanning an insect but not a mammal...
Autores principales: | Smith, Katherine M., Nanda, Kavita, McCarl, Victoria, Spears, Carla J., Piper, Amanda, Ribeiro, Mariana, Quiles, Michelle, Briggs, Caitlin M., Thomas, Gwynneth S., Thomas, Malcolm E., Brown, Dennis T., Hernandez, Raquel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society of Tropical Medicine and Hygiene
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3516330/ https://www.ncbi.nlm.nih.gov/pubmed/22890035 http://dx.doi.org/10.4269/ajtmh.2012.12-0004 |
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