Ad35 and Ad26 Vaccine Vectors Induce Potent and Cross-Reactive Antibody and T-Cell Responses to Multiple Filovirus Species

Filoviruses cause sporadic but highly lethal outbreaks of hemorrhagic fever in Africa in the human population. Currently, no drug or vaccine is available for treatment or prevention. A previous study with a vaccine candidate based on the low seroprevalent adenoviruses 26 and 35 (Ad26 and Ad35) was s...

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Detalles Bibliográficos
Autores principales: Zahn, Roland, Gillisen, Gert, Roos, Anna, Koning, Marina, van der Helm, Esmeralda, Spek, Dirk, Weijtens, Mo, Grazia Pau, Maria, Radošević, Katarina, Weverling, Gerrit Jan, Custers, Jerome, Vellinga, Jort, Schuitemaker, Hanneke, Goudsmit, Jaap, Rodríguez, Ariane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3516506/
https://www.ncbi.nlm.nih.gov/pubmed/23236343
http://dx.doi.org/10.1371/journal.pone.0044115

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