STAT1 Mediates Oroxylin A Inhibition of iNOS and Pro-Inflammatory Cytokines Expression in Microglial BV-2 Cells

Microglia-mediated inflammation is implicated in pathogenesis of neurodegenerative diseases. Oroxylin A, a flavonoid isolated from Scutellariae baicalensis, has been shown to ameliorate microglia activation-mediated neurodegeneration in vivo. The molecular mechanism underlying the inhibitory effects...

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Detalles Bibliográficos
Autores principales: Liu, Po-Wen, Chen, Mei-Fang, Tsai, Andy Po-Yi, Lee, Tony J. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3516518/
https://www.ncbi.nlm.nih.gov/pubmed/23236370
http://dx.doi.org/10.1371/journal.pone.0050363

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3516518/
https://www.ncbi.nlm.nih.gov/pubmed/23236370
http://dx.doi.org/10.1371/journal.pone.0050363

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