True 3q Chromosomal Amplification in Squamous Cell Lung Carcinoma by FISH and aCGH Molecular Analysis: Impact on Targeted Drugs

Squamous lung carcinoma lacks specific “ad hoc” therapies. Amplification of chromosome 3q is the most common genomic aberration and this region harbours genes having role as novel targets for therapeutics. There is no standard definition on how to score and report 3q amplification. False versus true...

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Detalles Bibliográficos
Autores principales: Brunelli, Matteo, Bria, Emilio, Nottegar, Alessia, Cingarlini, Sara, Simionato, Francesca, Caliò, Anna, Eccher, Albino, Parolini, Claudia, Iannucci, Antonio, Gilioli, Eliana, Pedron, Serena, Massari, Francesco, Tortora, Giampaolo, Borze, Ioana, Knuutila, Sakari, Gobbo, Stefano, Santo, Antonio, Tondulli, Luca, Calabrò, Francesco, Martignoni, Guido, Chilosi, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3516520/
https://www.ncbi.nlm.nih.gov/pubmed/23236352
http://dx.doi.org/10.1371/journal.pone.0049689

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