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HIV-1 Expressing the Envelopes of Transmitted/Founder or Control/Reference Viruses Have Similar Infection Patterns of CD4 T-Cells in Human Cervical Tissue Ex Vivo

Recently, it was found that 80% of sexual HIV-1 transmissions are established by a single virion/viral genome. To investigate whether the transmitted/founder (T/F) viruses have specific biological properties favoring sexual transmission, we inoculated human cervical tissue explants with isogenic HIV...

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Detalles Bibliográficos
Autores principales:	Merbah, Melanie, Arakelyan, Anush, Edmonds, Tara, Ochsenbauer, Christina, Kappes, John C., Shattock, Robin J., Grivel, Jean-Charles, Margolis, Leonid B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3516523/ https://www.ncbi.nlm.nih.gov/pubmed/23236398 http://dx.doi.org/10.1371/journal.pone.0050839

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