Cargando…

A Yeast GSK-3 Kinase Mck1 Promotes Cdc6 Degradation to Inhibit DNA Re-Replication

Cdc6p is an essential component of the pre-replicative complex (pre-RC), which binds to DNA replication origins to promote initiation of DNA replication. Only once per cell cycle does DNA replication take place. After initiation, the pre-RC components are disassembled in order to prevent re-replicat...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ikui, Amy E., Rossio, Valentina, Schroeder, Lea, Yoshida, Satoshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3516531/ https://www.ncbi.nlm.nih.gov/pubmed/23236290 http://dx.doi.org/10.1371/journal.pgen.1003099

Ejemplares similares

Cdc6 degradation requires phosphodegron created by GSK-3 and Cdk1 for SCF(Cdc4) recognition in Saccharomyces cerevisiae
por: Al-Zain, Amr, et al.
Publicado: (2015)

The budding yeast GSK-3 homologue Mck1 is an essential component of the spindle position checkpoint
por: Rathi, Siddhi, et al.
Publicado: (2022)

The Yeast GSK-3 Homologue Mck1 Is a Key Controller of Quiescence Entry and Chronological Lifespan
por: Quan, Zhenzhen, et al.
Publicado: (2015)

Spatial regulation of Cdc55–PP2A by Zds1/Zds2 controls mitotic entry and mitotic exit in budding yeast
por: Rossio, Valentina, et al.
Publicado: (2011)

Mck1 kinase is a new player in the DNA damage checkpoint pathway
por: Sanvisens Delgado, Nerea, et al.
Publicado: (2019)

Correction: Mck1 kinase is a new player in the DNA damage checkpoint pathway
Publicado: (2020)

Chronological Lifespan in Yeast Is Dependent on the Accumulation of Storage Carbohydrates Mediated by Yak1, Mck1 and Rim15 Kinases
por: Cao, Lu, et al.
Publicado: (2016)

SCF(Cyclin F)-dependent degradation of CDC6 suppresses DNA re-replication
por: Walter, David, et al.
Publicado: (2016)

The budding yeast PP2A(Cdc55) protein phosphatase prevents the onset of anaphase in response to morphogenetic defects
por: Chiroli, Elena, et al.
Publicado: (2007)

The Viral Chemokine MCK-2 of Murine Cytomegalovirus Promotes Infection as Part of a gH/gL/MCK-2 Complex
por: Wagner, Felicia M., et al.
Publicado: (2013)

Mck1 defines a key S-phase checkpoint effector in response to various degrees of replication threats
por: Li, Xiaoli, et al.
Publicado: (2019)

Tryptophan confers resistance to SDS-associated cell membrane stress in Saccharomyces cerevisiae
por: Schroeder, Lea, et al.
Publicado: (2019)

Cdc6 is sequentially regulated by PP2A-Cdc55, Cdc14, and Sic1 for origin licensing in S. cerevisiae
por: Philip, Jasmin, et al.
Publicado: (2022)

ORCA is regulated by ubiquitin-mediated degradation to control Orc2 function
por: Ikui, Amy E.
Publicado: (2012)

Zds1/Zds2–PP2A(Cdc55) complex specifies signaling output from Rho1 GTPase
por: Jonasson, Erin M., et al.
Publicado: (2016)

Claspin recruits Cdc7 kinase for initiation of DNA replication in human cells
por: Yang, Chi-Chun, et al.
Publicado: (2016)

Quantitative proteome and phosphoproteome datasets of DNA replication and mitosis in Saccharomyces cerevisiae
por: Rossio, Valentina, et al.
Publicado: (2022)

Localization of Cdc7 Protein Kinase During DNA Replication in Saccharomyces cerevisiae
por: Rossbach, Daniel, et al.
Publicado: (2017)

Hypoxic activation of ATR and the suppression of the initiation of DNA replication through cdc6 degradation
por: Martin, Leenus, et al.
Publicado: (2011)

Control of pre-replicative complex during the division cycle in Chlamydomonas reinhardtii
por: Ikui, Amy E., et al.
Publicado: (2021)

Up-regulation of the Cdc42 GTPase limits the replicative life span of budding yeast
por: Kang, Pil Jung, et al.
Publicado: (2022)

The MAPKKK CgMck1 Is Required for Cell Wall Integrity, Appressorium Development, and Pathogenicity in Colletotrichum gloeosporioides
por: Fang, Yu-Lan, et al.
Publicado: (2018)

Cdc6 ATPase activity disengages Cdc6 from the pre-replicative complex to promote DNA replication
por: Chang, FuJung, et al.
Publicado: (2015)

Checkpoint effects and telomere amplification during DNA re-replication in fission yeast
por: Mickle, Katie L, et al.
Publicado: (2007)

p34cdc2 acts as a lamin kinase in fission yeast
Publicado: (1991)

Comparative Proteomic Analysis of Two Commonly Used Laboratory Yeast Strains: W303 and BY4742
por: Rossio, Valentina, et al.
Publicado: (2023)

CDC48 function during TMV infection: Regulation of virus movement and replication by degradation?
por: Niehl, Annette, et al.
Publicado: (2013)

Kinetochores Coordinate Pericentromeric Cohesion and Early DNA Replication by Cdc7-Dbf4 Kinase Recruitment
por: Natsume, Toyoaki, et al.
Publicado: (2013)

CDC7 kinase (DDK) inhibition disrupts DNA replication leading to mitotic catastrophe in Ewing sarcoma
por: Martin, Jeffrey C., et al.
Publicado: (2022)

Mouse Cytomegalovirus Differentially Exploits Cell Surface Glycosaminoglycans in a Cell Type-Dependent and MCK-2-Independent Manner
por: Pontejo, Sergio M, et al.
Publicado: (2019)

Long-term muscle-specific overexpression of DOK7 in mice using AAV9-tMCK-DOK7
por: Huang, Yu-Ting, et al.
Publicado: (2023)

Computational modeling of chromosome re-replication in mutant strains of fission yeast
por: Novák, Béla, et al.
Publicado: (2021)

Cdt1 degradation to prevent DNA re-replication: conserved and non-conserved pathways
por: Kim, Youngjo, et al.
Publicado: (2007)

Cdc14 phosphatase directs centrosome re-duplication at the meiosis I to meiosis II transition in budding yeast
por: Fox, Colette, et al.
Publicado: (2017)

The RSC chromatin-remodeling complex influences mitotic exit and adaptation to the spindle assembly checkpoint by controlling the Cdc14 phosphatase
por: Rossio, Valentina, et al.
Publicado: (2010)

Deviation of the typical AAA substrate-threading pore prevents fatal protein degradation in yeast Cdc48
por: Esaki, Masatoshi, et al.
Publicado: (2017)

The structure of ORC–Cdc6 on an origin DNA reveals the mechanism of ORC activation by the replication initiator Cdc6
por: Feng, Xiang, et al.
Publicado: (2021)

Cdc18/CDC6 activates the Rad3-dependent checkpoint in the fission yeast
por: Fersht, Naomi, et al.
Publicado: (2007)

Turnover and bypass of p21-activated kinase during Cdc42-dependent MAPK signaling in yeast
por: González, Beatriz, et al.
Publicado: (2023)

MCK1 is a novel regulator of myo-inositol phosphate synthase (MIPS) that is required for inhibition of inositol synthesis by the mood stabilizer valproate
por: Yu, Wenxi, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_ifjom963mjduv10diu8rgbih56