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Enrichment of Mutations in Multiple DNA Sequences Using COLD-PCR in Emulsion

BACKGROUND: Multiplex detection of low-level mutant alleles in the presence of wild-type DNA would be useful for several fields of medicine including cancer, pre-natal diagnosis and infectious diseases. COLD-PCR is a recently developed method that enriches low-level mutations during PCR cycling, thu...

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Detalles Bibliográficos
Autores principales:	Castellanos-Rizaldos, Elena, Milbury, Coren Audrey, Makrigiorgos, G. Mike
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3516544/ https://www.ncbi.nlm.nih.gov/pubmed/23236486 http://dx.doi.org/10.1371/journal.pone.0051362

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