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Dissection of a Quantitative Trait Locus for PR Interval Duration Identifies Tnni3k as a Novel Modulator of Cardiac Conduction
Atrio-ventricular conduction disease is a common feature in Mendelian rhythm disorders associated with sudden cardiac death and is characterized by prolongation of the PR interval on the surface electrocardiogram (ECG). Prolongation of the PR interval is also a strong predictor of atrial fibrillatio...
Autores principales: | Lodder, Elisabeth M., Scicluna, Brendon P., Milano, Annalisa, Sun, Albert Y., Tang, Hao, Remme, Carol Ann, Moerland, Perry D., Tanck, Michael W. T., Pitt, Geoffrey S., Marchuk, Douglas A., Bezzina, Connie R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3516546/ https://www.ncbi.nlm.nih.gov/pubmed/23236294 http://dx.doi.org/10.1371/journal.pgen.1003113 |
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