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Sensitivity Analysis of Flux Determination in Heart by H(2) (18)O -provided Labeling Using a Dynamic Isotopologue Model of Energy Transfer Pathways

To characterize intracellular energy transfer in the heart, two organ-level methods have frequently been employed: [Image: see text] inversion and saturation transfer, and dynamic [Image: see text] labeling. Creatine kinase (CK) fluxes obtained by following oxygen labeling have been considerably sma...

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Detalles Bibliográficos
Autores principales: Schryer, David W., Peterson, Pearu, Illaste, Ardo, Vendelin, Marko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3516558/
https://www.ncbi.nlm.nih.gov/pubmed/23236266
http://dx.doi.org/10.1371/journal.pcbi.1002795