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Sensitivity Analysis of Flux Determination in Heart by H(2) (18)O -provided Labeling Using a Dynamic Isotopologue Model of Energy Transfer Pathways
To characterize intracellular energy transfer in the heart, two organ-level methods have frequently been employed: [Image: see text] inversion and saturation transfer, and dynamic [Image: see text] labeling. Creatine kinase (CK) fluxes obtained by following oxygen labeling have been considerably sma...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3516558/ https://www.ncbi.nlm.nih.gov/pubmed/23236266 http://dx.doi.org/10.1371/journal.pcbi.1002795 |