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The GM2 Glycan Serves as a Functional Coreceptor for Serotype 1 Reovirus
Viral attachment to target cells is the first step in infection and also serves as a determinant of tropism. Like many viruses, mammalian reoviruses bind with low affinity to cell-surface carbohydrate receptors to initiate the infectious process. Reoviruses disseminate with serotype-specific tropism...
Autores principales: | Reiss, Kerstin, Stencel, Jennifer E., Liu, Yan, Blaum, Bärbel S., Reiter, Dirk M., Feizi, Ten, Dermody, Terence S., Stehle, Thilo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3516570/ https://www.ncbi.nlm.nih.gov/pubmed/23236285 http://dx.doi.org/10.1371/journal.ppat.1003078 |
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