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Clofazimine Modulates the Expression of Lipid Metabolism Proteins in Mycobacterium leprae-Infected Macrophages
Mycobacterium leprae (M. leprae) lives and replicates within macrophages in a foamy, lipid-laden phagosome. The lipids provide essential nutrition for the mycobacteria, and M. leprae infection modulates expression of important host proteins related to lipid metabolism. Thus, M. leprae infection incr...
Autores principales: | Degang, Yang, Akama, Takeshi, Hara, Takeshi, Tanigawa, Kazunari, Ishido, Yuko, Gidoh, Masaichi, Makino, Masahiko, Ishii, Norihisa, Suzuki, Koichi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3516583/ https://www.ncbi.nlm.nih.gov/pubmed/23236531 http://dx.doi.org/10.1371/journal.pntd.0001936 |
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