The Ubiquitin-associated (UBA) 1 Domain of Schizosaccharomyces pombe Rhp23 Is Essential for the Recognition of Ubiquitin-proteasome System Substrates Both in Vitro and in Vivo

The ubiquitin-proteasome system is essential for maintaining a functional cell. Not only does it remove incorrectly folded proteins, it also regulates protein levels to ensure their appropriate spatial and temporal distribution. Proteins marked for degradation by the addition of Lys(48)-linked ubiqu...

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Detalles Bibliográficos
Autores principales: Medina, Bethan, Paraskevopoulos, Konstantinos, Boehringer, Jonas, Sznajder, Anna, Robertson, Morag, Endicott, Jane, Gordon, Colin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2012
Materias:
Molecular Biophysics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3516777/
https://www.ncbi.nlm.nih.gov/pubmed/23038266
http://dx.doi.org/10.1074/jbc.M112.419838

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