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Ultrasound-Mediated Gene Delivery with Cationic Versus Neutral Microbubbles: Effect of DNA and Microbubble Dose on In Vivo Transfection Efficiency

Objective: To assess the effect of varying microbubble (MB) and DNA doses on the overall and comparative efficiencies of ultrasound (US)-mediated gene delivery (UMGD) to murine hindlimb skeletal muscle using cationic versus neutral MBs. Materials and Methods: Cationic and control neutral MBs were ch...

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Detalles Bibliográficos
Autores principales: Panje, Cedric M., Wang, David S., Pysz, Marybeth A., Paulmurugan, Ramasamy, Ren, Ying, Tranquart, Francois, Tian, Lu, Willmann, Jürgen K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3516840/
https://www.ncbi.nlm.nih.gov/pubmed/23227124
http://dx.doi.org/10.7150/thno.4240