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A pedicled autologous choroid RPE patch: a technique to preserve perfusion

The aim of the study is to report a technique of a pedicled autologous choroid retinal pigment epithelium (RPE) patch that aims to preserve perfusion of the transplanted tissue. A case report of a patient with sudden vision deterioration due to submacular hemorrhage in age-related macular degenerati...

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Autores principales: Stopa, Marcin, Kocięcki, Jarosław, Rakowicz, Piotr, Dmitriew, Andrzej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3516983/
https://www.ncbi.nlm.nih.gov/pubmed/23256032
http://dx.doi.org/10.5114/wiitm.2011.28910
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author Stopa, Marcin
Kocięcki, Jarosław
Rakowicz, Piotr
Dmitriew, Andrzej
author_facet Stopa, Marcin
Kocięcki, Jarosław
Rakowicz, Piotr
Dmitriew, Andrzej
author_sort Stopa, Marcin
collection PubMed
description The aim of the study is to report a technique of a pedicled autologous choroid retinal pigment epithelium (RPE) patch that aims to preserve perfusion of the transplanted tissue. A case report of a patient with sudden vision deterioration due to submacular hemorrhage in age-related macular degeneration. The surgery involved a 180-degree peripheral retinectomy and the creation of a pedicled graft instead of an isolated one. Outcome measures included preoperative and postoperative visual acuity and optical coherence tomography scans at 1, 3, 6, 12 months and patch vascularization on postoperative indocyanine green angiography. Postoperatively the patch was positioned under the fovea with an intact pedicle. Indocyanine green angiography showed perfusion through the pedicle and patch vasculature on the third postoperative day. Best corrected visual acuity improved from 0.5/50 to 5/50 at 1 month and remained stable over 1 year follow-up. No choroidal neovascularization recurrence was observed. This case report demonstrates the feasibility of a pedicled RPE-choroid graft that is an alternative to a free isolated graft. Our modification of patch surgery, by demonstrating early perfusion, offers an advantage, similar to macular translocation, when photoreceptors are embedded in RPE and choroid with blood circulation immediately after the surgery.
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spelling pubmed-35169832012-12-19 A pedicled autologous choroid RPE patch: a technique to preserve perfusion Stopa, Marcin Kocięcki, Jarosław Rakowicz, Piotr Dmitriew, Andrzej Wideochir Inne Tech Maloinwazyjne Case Report The aim of the study is to report a technique of a pedicled autologous choroid retinal pigment epithelium (RPE) patch that aims to preserve perfusion of the transplanted tissue. A case report of a patient with sudden vision deterioration due to submacular hemorrhage in age-related macular degeneration. The surgery involved a 180-degree peripheral retinectomy and the creation of a pedicled graft instead of an isolated one. Outcome measures included preoperative and postoperative visual acuity and optical coherence tomography scans at 1, 3, 6, 12 months and patch vascularization on postoperative indocyanine green angiography. Postoperatively the patch was positioned under the fovea with an intact pedicle. Indocyanine green angiography showed perfusion through the pedicle and patch vasculature on the third postoperative day. Best corrected visual acuity improved from 0.5/50 to 5/50 at 1 month and remained stable over 1 year follow-up. No choroidal neovascularization recurrence was observed. This case report demonstrates the feasibility of a pedicled RPE-choroid graft that is an alternative to a free isolated graft. Our modification of patch surgery, by demonstrating early perfusion, offers an advantage, similar to macular translocation, when photoreceptors are embedded in RPE and choroid with blood circulation immediately after the surgery. Termedia Publishing House 2012-06-22 2012-08 /pmc/articles/PMC3516983/ /pubmed/23256032 http://dx.doi.org/10.5114/wiitm.2011.28910 Text en Copyright © 2012 Sekcja Wideochirurgii TChP http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial 3.0 Unported License, permitting all non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Stopa, Marcin
Kocięcki, Jarosław
Rakowicz, Piotr
Dmitriew, Andrzej
A pedicled autologous choroid RPE patch: a technique to preserve perfusion
title A pedicled autologous choroid RPE patch: a technique to preserve perfusion
title_full A pedicled autologous choroid RPE patch: a technique to preserve perfusion
title_fullStr A pedicled autologous choroid RPE patch: a technique to preserve perfusion
title_full_unstemmed A pedicled autologous choroid RPE patch: a technique to preserve perfusion
title_short A pedicled autologous choroid RPE patch: a technique to preserve perfusion
title_sort pedicled autologous choroid rpe patch: a technique to preserve perfusion
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3516983/
https://www.ncbi.nlm.nih.gov/pubmed/23256032
http://dx.doi.org/10.5114/wiitm.2011.28910
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