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Induction of heat shock protein 70 (Hsp70) prevents neuregulin-induced demyelination by enhancing the proteasomal clearance of c-Jun

Modulating molecular chaperones is emerging as an attractive approach to treat neurodegenerative diseases associated with protein aggregation, DPN (diabetic peripheral neuropathy) and possibly, demyelinating neuropathies. KU-32 [N-(7-((2R,3R,4S,5R)-3,4-dihydroxy-5-methoxy-6,6-dimethyl-tetrahydro-2H-...

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Detalles Bibliográficos
Autores principales:	Li, Chengyuan, Ma, Jiacheng, Zhao, Huiping, Blagg, Brian S.J, Dobrowsky, Rick T
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Neurochemistry 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3517131/ https://www.ncbi.nlm.nih.gov/pubmed/23240583 http://dx.doi.org/10.1042/20120047

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