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Molecular and cellular mechanisms of the age-dependency of opioid analgesia and tolerance
The age-dependency of opioid analgesia and tolerance has been noticed in both clinical observation and laboratory studies. Evidence shows that many molecular and cellular events that play essential roles in opioid analgesia and tolerance are actually age-dependent. For example, the expression and fu...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3517334/ https://www.ncbi.nlm.nih.gov/pubmed/22612909 http://dx.doi.org/10.1186/1744-8069-8-38 |