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Molecular and cellular mechanisms of the age-dependency of opioid analgesia and tolerance

The age-dependency of opioid analgesia and tolerance has been noticed in both clinical observation and laboratory studies. Evidence shows that many molecular and cellular events that play essential roles in opioid analgesia and tolerance are actually age-dependent. For example, the expression and fu...

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Detalles Bibliográficos
Autores principales: Zhao, Jing, Xin, Xin, Xie, Guo-xi, Palmer, Pamela Pierce, Huang, Yu-guang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3517334/
https://www.ncbi.nlm.nih.gov/pubmed/22612909
http://dx.doi.org/10.1186/1744-8069-8-38