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Association of genetic variation in the NR1H4 gene, encoding the nuclear bile acid receptor FXR, with inflammatory bowel disease

BACKGROUND: Pathogenesis of inflammatory bowel diseases (IBD), ulcerative colitis (UC) and Crohn’s disease (CD), involves interaction between environmental factors and inappropriate immune responses in the intestine of genetically predisposed individuals. Bile acids and their nuclear receptor, FXR,...

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Detalles Bibliográficos
Autores principales:	Attinkara, Ragam, Mwinyi, Jessica, Truninger, Kaspar, Regula, Jaroslaw, Gaj, Pawel, Rogler, Gerhard, Kullak-Ublick, Gerd A, Eloranta, Jyrki J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3517390/ https://www.ncbi.nlm.nih.gov/pubmed/22929053 http://dx.doi.org/10.1186/1756-0500-5-461

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