Cargando…

Evaluation of the Zucker Diabetic Fatty (ZDF) Rat as a Model for Human Disease Based on Urinary Peptidomic Profiles

Representative animal models for diabetes-associated vascular complications are extremely relevant in assessing potential therapeutic drugs. While several rodent models for type 2 diabetes (T2D) are available, their relevance in recapitulating renal and cardiovascular features of diabetes in man is...

Descripción completa

Detalles Bibliográficos
Autores principales:	Siwy, Justyna, Zoja, Carlamaria, Klein, Julie, Benigni, Ariela, Mullen, Wiliam, Mayer, Bernd, Mischak, Harald, Jankowski, Joachim, Stevens, Robert, Vlahou, Antonia, Kossida, Sophia, Perco, Paul, Bahlmann, Ferdinand H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3517416/ https://www.ncbi.nlm.nih.gov/pubmed/23236474 http://dx.doi.org/10.1371/journal.pone.0051334

Ejemplares similares

Exploratory Study Analyzing the Urinary Peptidome of T2DM Patients Suggests Changes in ECM but Also Inflammatory and Metabolic Pathways Following GLP-1R Agonist Treatment
por: Lohia, Sonnal, et al.
Publicado: (2023)

Urine peptidome in combination with transcriptomics analysis highlights MMP7, MMP14 and PCSK5 for further investigation in chronic kidney disease
por: Petra, Eleni, et al.
Publicado: (2022)

Urine peptidome analysis in cardiorenal syndrome reflects molecular processes
por: Petra, Eleni, et al.
Publicado: (2021)

Glycosylation Analysis of Urinary Peptidome Highlights IGF2 Glycopeptides in Association with CKD
por: Lohia, Sonnal, et al.
Publicado: (2023)

Urinary peptidomic profiles to address age-related disabilities: a prospective population study
por: Martens, Dries S, et al.
Publicado: (2021)

Histological Evaluation of Diabetic Neurodegeneration in the Retina of Zucker Diabetic Fatty (ZDF) Rats
por: Szabó, Klaudia, et al.
Publicado: (2017)

Collagen-Derived Peptides in CKD: A Link to Fibrosis
por: Mavrogeorgis, Emmanouil, et al.
Publicado: (2021)

Myocardial impulse propagation is impaired in right ventricular tissue of Zucker Diabetic Fatty (ZDF) rats
por: Olsen, Kristine Boisen, et al.
Publicado: (2013)

Detailed Evaluation of Possible Ganglion Cell Loss in the Retina of Zucker Diabetic Fatty (ZDF) Rats
por: Hajdú, Rozina I., et al.
Publicado: (2019)

Urinary CE-MS peptide marker pattern for detection of solid tumors
por: Belczacka, Iwona, et al.
Publicado: (2018)

Author Correction: Urinary CE-MS peptide marker pattern for detection of solid tumors
por: Belczacka, Iwona, et al.
Publicado: (2019)

Add-On Cyclic Angiotensin-(1-7) with Cyclophosphamide Arrests Progressive Kidney Disease in Rats with ANCA Associated Glomerulonephritis
por: Cerullo, Domenico, et al.
Publicado: (2022)

Urine Peptidome Analysis Identifies Common and Stage-Specific Markers in Early Versus Advanced CKD
por: Hobson, Sam, et al.
Publicado: (2023)

Electrocardiographic changes with the onset of diabetes and the impact of aerobic exercise training in the Zucker Diabetic Fatty (ZDF) rat
por: VanHoose, Lisa, et al.
Publicado: (2010)

Urinary peptides provide information about the risk of mortality across a spectrum of diseases and scenarios
por: Keller, Felix, et al.
Publicado: (2023)

Sirtuin 3 Deficiency Aggravates Kidney Disease in Response to High-Fat Diet through Lipotoxicity-Induced Mitochondrial Damage
por: Locatelli, Monica, et al.
Publicado: (2022)

Urinary peptidomics analysis reveals proteases involved in diabetic nephropathy
por: Krochmal, Magdalena, et al.
Publicado: (2017)

Cardioprotective Role of BGP-15 in Ageing Zucker Diabetic Fatty Rat (ZDF) Model: Extended Mitochondrial Longevity
por: Kozma, Mate, et al.
Publicado: (2022)

Protective effects of GuanXinNing tablet (GXNT) on diabetic encephalopathy in zucker diabetic obesity (ZDF) rats
por: Li, Yajing, et al.
Publicado: (2023)

Renal Expression of FGF23 in Progressive Renal Disease of Diabetes and the Effect of Ace Inhibitor
por: Zanchi, Cristina, et al.
Publicado: (2013)

Low Nephron Number Induced by Maternal Protein Restriction Is Prevented by Nicotinamide Riboside Supplementation Depending on Sirtuin 3 Activation
por: Pezzotta, Anna, et al.
Publicado: (2022)

Protein Interactome of Muscle Invasive Bladder Cancer
por: Bhat, Akshay, et al.
Publicado: (2015)

Reproducibility Evaluation of Urinary Peptide Detection Using CE-MS
por: Mavrogeorgis, Emmanouil, et al.
Publicado: (2021)

Comparative proteome and peptidome analysis of the cephalic fluid secreted by Arapaima gigas (Teleostei: Osteoglossidae) during and outside parental care
por: Torati, Lucas S., et al.
Publicado: (2017)

The effect of a long-term treatment with cannabidiol-rich hemp extract oil on the adenosinergic system of the zucker diabetic fatty (ZDF) rat atrium
por: Viczjan, Gabor, et al.
Publicado: (2022)

Manipulating Sirtuin 3 pathway ameliorates renal damage in experimental diabetes
por: Locatelli, Monica, et al.
Publicado: (2020)

Endothelial Glycocalyx of Peritubular Capillaries in Experimental Diabetic Nephropathy: A Target of ACE Inhibitor-Induced Kidney Microvascular Protection
por: Locatelli, Monica, et al.
Publicado: (2023)

Associations of urinary polymeric immunoglobulin receptor peptides in the context of cardio-renal syndrome
por: He, Tianlin, et al.
Publicado: (2020)

Urinary Peptidomics and Pulse Wave Velocity: The African-PREDICT Study
por: de Beer, Dalene, et al.
Publicado: (2023)

Renal Primordia Activate Kidney Regenerative Events in a Rat Model of Progressive Renal Disease
por: Imberti, Barbara, et al.
Publicado: (2015)

MicroRNA-184 is a downstream effector of albuminuria driving renal fibrosis in rats with diabetic nephropathy
por: Zanchi, Cristina, et al.
Publicado: (2017)

Comparison of Depletion Strategies for the Enrichment of Low-Abundance Proteins in Urine
por: Filip, Szymon, et al.
Publicado: (2015)

Prediction of Methionine and Homocysteine levels in Zucker diabetic fatty (ZDF) rats as a T2DM animal model after consumption of a Methionine-rich diet
por: Han, Nayoung, et al.
Publicado: (2018)

Machine Learning-Based Urine Peptidome Analysis to Predict and Understand Mechanisms of Progression to Kidney Failure
por: Massy, Ziad A., et al.
Publicado: (2022)

BcCluster: A Bladder Cancer Database at the Molecular Level
por: Bhat, Akshay, et al.
Publicado: (2016)

Proteomic Candidate Biomarkers of Drug-Induced Nephrotoxicity in the Rat
por: Rouse, Rodney, et al.
Publicado: (2012)

A previously unrecognized role of C3a in proteinuric progressive nephropathy
por: Morigi, Marina, et al.
Publicado: (2016)

'Brukin2D': a 2D visualization and comparison tool for LC-MS data
por: Tsagkrasoulis, Dimosthenis, et al.
Publicado: (2009)

Shiga Toxin 2 Triggers C3a-Dependent Glomerular and Tubular Injury through Mitochondrial Dysfunction in Hemolytic Uremic Syndrome
por: Buelli, Simona, et al.
Publicado: (2022)

Increased Renal Versican Expression Is Associated with Progression of Chronic Kidney Disease
por: Rudnicki, Michael, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_o2ibgr3c8dvi9ga304tr9iulio