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Localized Intestinal Radiation and Liquid Diet Enhance Survival and Permit Evaluation of Long-Term Intestinal Responses to High Dose Radiation in Mice
BACKGROUND: In vivo studies of high dose radiation-induced crypt and intestinal stem cell (ISC) loss and subsequent regeneration are typically restricted to 5–8 days after radiation due to high mortality and immune failure. This study aimed to develop murine radiation models of complete crypt loss t...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3517426/ https://www.ncbi.nlm.nih.gov/pubmed/23236468 http://dx.doi.org/10.1371/journal.pone.0051310 |