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Localized Intestinal Radiation and Liquid Diet Enhance Survival and Permit Evaluation of Long-Term Intestinal Responses to High Dose Radiation in Mice

BACKGROUND: In vivo studies of high dose radiation-induced crypt and intestinal stem cell (ISC) loss and subsequent regeneration are typically restricted to 5–8 days after radiation due to high mortality and immune failure. This study aimed to develop murine radiation models of complete crypt loss t...

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Detalles Bibliográficos
Autores principales:	Van Landeghem, Laurianne, Blue, Randall Eric, Dehmer, Jeffrey J., Henning, Susan J., Helmrath, Michael A., Lund, Pauline Kay
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3517426/ https://www.ncbi.nlm.nih.gov/pubmed/23236468 http://dx.doi.org/10.1371/journal.pone.0051310

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