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Direct Association of Unfolded Proteins with Mammalian ER Stress Sensor, IRE1β

IRE1, an ER-localized transmembrane protein, plays a central role in the unfolded protein response (UPR). IRE1 senses the accumulation of unfolded proteins in its luminal domain and transmits a signal to the cytosolic side through its kinase and RNase domains. Although the downstream pathways mediat...

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Detalles Bibliográficos
Autores principales:	Oikawa, Daisuke, Kitamura, Akira, Kinjo, Masataka, Iwawaki, Takao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3517461/ https://www.ncbi.nlm.nih.gov/pubmed/23236464 http://dx.doi.org/10.1371/journal.pone.0051290

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