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4-Chloropropofol enhances chloride currents in human hyperekplexic and artificial mutated glycine receptors

BACKGROUND: The mammalian neurological disorder hereditary hyperekplexia can be attributed to various mutations of strychnine sensitive glycine receptors. The clinical symptoms of “startle disease” predominantly occur in the newborn leading to convulsive hypertonia and an exaggerated startle respons...

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Detalles Bibliográficos
Autores principales:	de la Roche, Jeanne, Leuwer, Martin, Krampfl, Klaus, Haeseler, Gertrud, Dengler, Reinhard, Buchholz, Vanessa, Ahrens, Jörg
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3517478/ https://www.ncbi.nlm.nih.gov/pubmed/23006332 http://dx.doi.org/10.1186/1471-2377-12-104

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