Residual Baculovirus in Insect Cell-Derived Influenza Virus-Like Particle Preparations Enhances Immunogenicity

Influenza virus-like particles are currently evaluated in clinical trials as vaccine candidates for influenza viruses. Most commonly they are produced in baculovirus- or mammalian- expression systems. Here we used different vaccination schemes in order to systematically compare virus-like particle p...

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Detalles Bibliográficos
Autores principales: Margine, Irina, Martinez-Gil, Luis, Chou, Yi-ying, Krammer, Florian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3517492/
https://www.ncbi.nlm.nih.gov/pubmed/23236516
http://dx.doi.org/10.1371/journal.pone.0051559

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