Analysis of C. elegans NR2E nuclear receptors defines three conserved clades and ligand-independent functions

BACKGROUND: The nuclear receptors (NRs) are an important class of transcription factors that are conserved across animal phyla. Canonical NRs consist of a DNA-binding domain (DBD) and ligand-binding domain (LBD). While most animals have 20–40 NRs, nematodes of the genus Caenorhabditis have experienc...

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Detalles Bibliográficos
Autores principales: Weber, Katherine P, Alvaro, Christopher G, Baer, G Michael, Reinert, Kristy, Cheng, Genevieve, Clever, Sheila, Wightman, Bruce
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3517510/
https://www.ncbi.nlm.nih.gov/pubmed/22690911
http://dx.doi.org/10.1186/1471-2148-12-81

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