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Long-term effects of cranial irradiation and intrathecal chemotherapy in treatment of childhood leukemia: a MEG study of power spectrum and correlated cognitive dysfunction

BACKGROUND: Prophylaxis to prevent relapses in the central nervous system after childhood acute lymphoblastic leukemia (ALL) used to consist of both intrathecal chemotherapy (CT) and cranial irradiation (CRT). CRT was mostly abolished in the eighties because of its neurotoxicity, and replaced with m...

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Detalles Bibliográficos
Autores principales: Daams, Marita, Schuitema, Ilse, van Dijk, Bob W, van Dulmen-den Broeder, Eline, Veerman, Anjo JP, van den Bos, Cor, de Sonneville, Leo MJ
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3517522/
https://www.ncbi.nlm.nih.gov/pubmed/22928913
http://dx.doi.org/10.1186/1471-2377-12-84