Histone Demethylase Jumonji D3 (JMJD3) as a Tumor Suppressor by Regulating p53 Protein Nuclear Stabilization

Histone methylation regulates normal stem cell fate decisions through a coordinated interplay between histone methyltransferases and demethylases at lineage specific genes. Malignant transformation is associated with aberrant accumulation of repressive histone modifications, such as polycomb mediate...

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Detalles Bibliográficos
Autores principales: Ene, Chibawanye I., Edwards, Lincoln, Riddick, Gregory, Baysan, Mehmet, Woolard, Kevin, Kotliarova, Svetlana, Lai, Chen, Belova, Galina, Cam, Maggie, Walling, Jennifer, Zhou, Ming, Stevenson, Holly, Kim, Hong Sug, Killian, Keith, Veenstra, Timothy, Bailey, Rolanda, Song, Hua, Zhang, Wei, Fine, Howard A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3517524/
https://www.ncbi.nlm.nih.gov/pubmed/23236496
http://dx.doi.org/10.1371/journal.pone.0051407

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